Pope Benedict XVI will deliver the Thought For The Day on BBC Radio 4 on Christmas Eve morning.
His Christmas message to the British people follows a visit to the UK in September - the first official state visit to the country by a pontiff.
It is an unprecedented move, as Pope Benedict is not thought to have presented material specifically written for a radio or TV audience before.
The Pope recorded Thought For The Day in Rome on Wednesday.
Gwyneth Williams, the controller of Radio 4, said: "I'm delighted Pope Benedict is sharing his Christmas message with the Radio 4 audience."
"It's significant that the Pope has chosen Thought For The Day to give his first personally scripted broadcast - and what better time to do so than on the eve of the biggest celebration on the Christian calendar."
Thought For The Day is broadcast within the Today programme at 0745 from Monday to Saturday.
It offers approximately three minutes of personal reflection from faith leaders and believers of a variety of religious denominations.
(Originally posted on BBC News.)